Preclinical evaluation is a dynamic field that is constantly evolving in response to new scientific discoveries, technological advances and changing societal needs. This article takes a look at the latest trends and innovations in preclinical evaluation.

   The growing importance of in silico research

  One of the key trends in preclinical evaluation is the rise of in silico studies, which are conducted with the help of computers. Computer models can be used to predict the effects of potential drugs, assess their interactions with biological targets, and simulate their effects on the body. This trend is being driven by advances in biomedical informatics and the availability of increasingly large biological data sets.

   Using organoids and other 3D models

  Another important trend is the growing use of organoids and other 3D models in in vitro research. Organoids, which are miniaturized versions of organs, can better represent the complex interactions between different cell types than traditional 2D models. They can also facilitate studies on the effects of drugs on specific organs or tissues.

   Use of CRISPR technology

  CRISPR gene editing technology has become an indispensable tool in preclinical evaluation. Thanks to CRISPR, scientists can precisely modify genes in cells or organisms, which allows for a more accurate study of drug mechanisms, as well as the development of new gene therapies.

   Application of artificial intelligence (AI)

  Artificial intelligence (AI) is becoming increasingly important in preclinical evaluation. AI can help speed up the drug discovery process, predict drug interactions, analyze large clinical data sets, and other aspects of preclinical evaluation.

   Summary

  Preclinical evaluation is a field that is constantly evolving due to new scientific discoveries and technological advances. The rise of in silico testing, the use of organoids and other 3D models, the application of CRISPR technology and artificial intelligence are just some of the trends and innovations that are shaping contemporary preclinical evaluation. Thanks to these innovations, preclinical evaluation is becoming more precise, efficient and patient-focused.